崔紅娟,博士、西南大學(xué)蠶學(xué)與系統(tǒng)生物學(xué)研究所教授、博士生導(dǎo)師。從事細(xì)胞生物學(xué)特別是干細(xì)胞生物學(xué)領(lǐng)域科學(xué)研究及人才培養(yǎng)。

性別

民族

漢族

國(guó)籍

中國(guó)

畢業(yè)院校

西南大學(xué)

職業(yè)

教育工作者

職稱

教授

簡(jiǎn)歷

1988-2000年在西南大學(xué)完成本科、碩士、博士學(xué)習(xí)。

2000-2001年,第四軍醫(yī)大學(xué)博士后,

2001-2005年,俄亥俄醫(yī)學(xué)院生化及腫瘤生物學(xué)助理研究員;

2005-2009年,俄亥俄醫(yī)學(xué)院生化及腫瘤生物學(xué)助理教授;

2009-2010年,美國(guó)克利夫蘭研究診所干細(xì)胞生物學(xué)及再生醫(yī)學(xué)助理教授;

2010-2014 重慶市百人計(jì)劃,

2010-2014成為重慶市巴渝學(xué)者。

2010-至今,西南大學(xué)教授

在美國(guó)期間,先后主持和參與了NIH、美國(guó)癌癥協(xié)會(huì)和俄亥俄州多項(xiàng)課題的研究。在Nature Cel. Bio.,J.Biol.Chem.,Am.J.Pathol.,Molcancer Ther.等國(guó)際著名雜志發(fā)表高水平學(xué)術(shù)論文10余篇。

主要科研領(lǐng)域與方向

腫瘤生物學(xué)及腫瘤干細(xì)胞的研究;

家蠶、昆蟲干細(xì)胞生物學(xué)發(fā)育及細(xì)胞生物學(xué)領(lǐng)域;

腫瘤藥效評(píng)價(jià)及轉(zhuǎn)化醫(yī)學(xué)。

代表性論文

Mao L, Ding J, Zha Y, Yang L, McCarthy B, King W,

Hongjuan Cui

, Ding H. HOXC9 links cell cycle exit and neuronal differentiation and is a prognostic marker in neuroblastoma. Cancer Res., 2011 inpress.Yang L,

Hongjuan Cui

, Wang Z, Zhang B, Ding J, Liu L, Ding HF. Loss of negative feedback control of nuclear factor-kappa B2 activity in lymphocytes leads to fatal lung inflammation. Am J pathol, 2010 Apr 2. Epib ahead of print.Yang H, Zhu L, Ebraheim NA, Liu X, Castillo S, Tang T, Liu J,

Hongjuan Cui.

2009, Analysis of risk factors for recurrence after the resection of sacral chordoma combined with embolization.Spine J. Sep30.Ling Mao, Yuan-Peng Xia, Yu-Nan Zhou, Ruo-Lian Dai, Xue Yang, Shu-Jie Duan, Xian Qiao, Yuan-Wu Mei, Bo Hu and

Hongjuan Cui

, 2009 Acritical role of Sonic Hedgehog signaling in maintaining the tumorigenicity of neuroblastoma cellsCancer Sci.Jun 26. [Epub ahead of print]Goleeta Alam,

Hongjuan Cui(co-principal author),

Huilin Shi, Jane Ding, ling Mao, William A. Maltese, and Han-Fei Ding, MYCN promotes the expansion of Phox2B-positive neuronal progenitors to drive neuroblastoma development. Am J Pathol.2009 Aug; 175(2):856-66. Epub 2009 Jul 16.Huilin Shi,

Hongjuan Cui

, Goleeta Alam, William Gunning, Andrea Nestor, David Giovannucci, Ming Zhang, Han-Fei Ding, 2008. nestin expression defines both glial and neuronal progenitors in postnatal sympathetic Ganglia, Journal of Comparative Neurology, 508: 867-878.

Hongjuan Cui

, Bo Hu, Tai Li, Jun Ma, Goleeta Alam, William T Gunning, and Han-Fei Ding, 2007. Bmi-1 is essential for the tumorigenicity of Neuroblastoma cells, American Journal of Pathology, 170 (4): 1370-1378.

Hongjuan Cui

, Jun Ma, Jane Ding, Tai Li, Goleeta Alam, and Han-Fei Ding, 2006, Bmi-1 regulates differentiation and clonogenic self-renewal of I-type neuroblastoma cells in a concentration-dependent manner, Journal of Biological Chemistry, 281 (45): 34696-34704.

Hongjuan Cui

, Tai Li, Han-Fei Ding, 2005, Linking of N-Myc to death receptor machinery in neuroblastoma cells, Journal of Biological Chemistry, 280: 9474-9481Yongqing Wang,

Hongjuan Cui (Co-principal author

), Allen Schroering, Jane L. Ding, William S. lane, Ga?l McGill, David E. Fisher and Han-Fei Ding. 2002. NF-?B2 p100 is a pro-apoptotic protein with anti-oncogenic function. Nature Cell Biology. 4(11): 888-93.

Hongjuan Cui

, Allen Schroering, and Han-Fei Ding. 2002. p53 mediated DNA damaging drug-induced apoptosis through a caspase-9-dependent pathway in Sh-SY5Y neuroblastoma cells. Molecular Cancer Therapeutics. 1: 679-686.